Surgical oncologist (liver cancers), cancer researcher, looking for better and less toxic ways to treat cancer, soccer lover (Go team USA!), live and love life!
Dr. Steven A. Curley specializes in providing surgical care for patients with hepatobiliary and pancreatic malignancies. As our chief of surgical oncology and cancer center associate director, he leads efforts at Baylor College of Medicine (BCM) and on the McNair campus to build a world-class, multidisciplinary surgical oncology program with significant national and international outreach and stature.
Dr. Curley has been leading a basic sciences laboratory for 22 years. Currently, his research centers on the design, bench testing, and clinical study of novel noninvasive radiofrequency (RF) field treatment devices. Having developed two FDA-approved devices for invasive radiofrequency ablation needles to treat unresectable liver cancers, his current studies focus on targeted delivery of metallic or semiconducting nanoparticles that release heat under RF field induction to cause thermal cytotoxicity in cancer cells. His group has also performed complex physicochemical measurements of nanoparticles, and has conjugated them to antibodies, peptides, and pharmacologic agents to target cancer cells. He hopes to test these novel treatments in human clinical trials at BCM within the next two to three years, pending FDA approval.
- Professor of Surgery and Chief: Division of Surgical Oncology Baylor College of Medicine Houston, United States
- Olga Keith Wiess Chair of Surgery: Baylor College of Medicine
- Associate Director for Clinical Affairs: Dan L Duncan Comprehensive Cancer Center
- Oncology Service Line Chief: CHI St. Luke’s Medical Center
- Professor of Mechanical Engineering and Materials Science: Rice University
- Fellowship from The University of Texas, M.D. Anderson Cancer Center: Houston, Texas, United States
- Residency from University of New Mexico Hospitals: Albuquerque, New Mexico, United States
- M.D. from The University of Texas Medical School at Houston: Houston, Texas, United States
- American Board of Surgery
Honors & Awards
- Top 1% of Physicians: US News & World Report, 2012-2015
- Patients’ Choice Award: America’s Most Compassionate Doctors, 2010-2015
- Best Doctors in America
- America’s Top Doctors: Castle Connolly
- Surgical Oncology
- Liver, bile duct, and gallbladder cancer surgery
- Neuroendocrine tumor surgery
- Colorectal cancer surgery
- American College of Surgeons
- American Society of Clinical Oncology
- Society for Surgery of the Alimentary Tract
- Southwest Oncology Group
- American Hepato-Pancreato-Biliary Association Member, Committee on Emerging Te
- Institute of Medicine National Cancer Policy Forum
- American Association of Cancer Research
- Harris County Medical Society
- Texas Medical Association
- Andreou A, Aloia TA, Brouquet A, Dickson PV, Zimmitti G, Maru DM, Kopetz S, Loyer EM, Curley SA, Abdalla EK, Vauthey JN. “Margin Status Remains an Important Determinant of Survival After Surgical Resection of Colorectal Liver Metastases in the Era of Modern Chemotherapy.” Ann Surg. 2013;257(6):1079-88.
- Corr SJ, Cisneros BT, Green L, Raoof M, Curley SA. “Protocols for Assessing Radiofrequency Interactions with Gold Nanoparticles and Biological Systems for Non-invasive Hyperthermia Cancer Therapy.” J Vis Exp. 2013
- 4. Shindoh J, Loyer EM, Kopetz S, Boonsirikamchai P, Maru DM, Chun YS, Zimmitti G, Curley SA, Charnsangavej C, Aloia TA, Vauthey JN. “Optimal morphologic response to preoperative chemotherapy: an alternate outcome end point before resection of hepatic colorectal metastases.” J Clin Oncol. 2012;30(36):4566-72.
- 3. Sahin IH, Shama MA, Tanaka M, Abbruzzese JL, Curley SA, Hassan M, Li D. “Association of diabetes and perineural invasion in pancreatic cancer.” Cancer Med. 2012;1(3):357-62.
- 2. Raoof M, Corr SJ, Kaluarachchi WD, Massey KL, Briggs K, Zhu C, Cheney MA, Wilson LJ, Curley SA. “Stability of antibody-conjugated gold nanoparticles in the endolysosomal nanoenvironment: Implications for noninvasive radiofrequency-based cancer therapy.” Nanomedicine. 2012;8(7):1096-105.
- 1. Andreou A, Kopetz S, Maru DM, Chen SS, Zimmitti G, Brouquet A, Shindoh J, Curley SA, Garrett C, Overman MJ, Aloia TA, Vauthey JN. “Adjuvant chemotherapy with FOLFOX for primary colorectal cancer is associated with increased somatic gene mutations and inferior survival in patients undergoing hepatectomy for metachronous liver metastases.” Ann Surg. 2012;256(4):642-650.
Thanks Steve for all that you do!
In 2011 my husband and I came to MDA after a diagnosis of liver cancer which was made by our doctor in El Paso. After a week of testing and much prayer, you came into our hospital roon telling my husband that you had a curve for him. You then told him this liver cancer originated in the pancrease and with my husband, an attorney, who practiced defense medical malpractice and had “saved” many doctors in our community from unjust decisions…yes, he was good and he knew well the severity of the diagnoses. Very quietly and calmly Frank ask if there was any treatment to which you said “no”….just go home. I shall always appreciate your truthfulnees at that time. We left the next day, our three grown and married children took leaves of absenses and they, their husbands, wives and children arrived for two glorious weeks of time together. Our neighor and close friend, an optomologist, gave a dinner in order for Frank to tell each of our friends the impact they had made on his life and see him for the last time. One amazing thing and gift from God was that he had no pain. He also had been diaagnosed the previous year with Parkinson’s and was, of course, spared that. Finally the greatest gift of all came one early morning several days before he died. As I took his blood pressure, he quietly looked at me and said, “I see the countinance of God”. At that point he described what he saw but revealed that words actually could not truly describe the glorious light and vision of Jesus. He saw family members, much younger, that had passed away. But the most amazing thing was his parents who held the hand of a beautiful little girl which Frank said must be his sister who died when his mother gave birth as the chord was around her neck.I could go on and on but it was beautiful and so comforting.Frank died within a 5 week period from beginning to end. During my grieving, I knew that God was walkiing with me and would always be with me. He has held true to that promise. I know your job is a hard one as the news is so ofter grim, but I wanted you to know how much both Frank and I appreiated your sincerity during that time. Frank was a great man in so many ways and truly, the love of my life! Thank you, Elizabeth Feuille
Thank you for your thoughtful and heartfelt note Elizabeth. Peace and blessings to you and your family, I remember Frank well and your story confirms he was a superb man.